Comparing Viagra with the other two phosphodiesterase type 5 (PDE-5) inhibitors.

Are you ready to combat erectile dysfunction but are not yet sure about the type of PDE-5 inhibitor to use? This is not an unusual problem. Viagra, the citrate salt of Sildenafil, is the most popular among the 3 PDE-5 inhibitors approved by the FDA. But don’t let popularity alone be the deciding factor for you. Before making the decision to buy Viagra cheap online, it is important to note that Cialis and Levitra, the other two PDE-5 inhibitors, are equally safe and highly effective, though they are not as popular as Viagra yet.

For starters, the three drugs, as phosphodiesterase type 5 inhibitors, are effective in relaxing the walls of the penile arteries, thus allowing for increased flow of blood into the corpus cavernosum of the penis and subsequently erection. Simultaneously occurring with the inhibition of PDE 5 is the increase in the level of cyclic guanosine monophosphate (cGMP).

During sexual arousal, the level of cyclic guanosine monophosphate is naturally increased by the penile tissue and this is a key factor in the relaxation of the arteries.

By contrast, the PDE-5 enzyme degrades the secretion of cGMP in most men suffering from E.D. When the penis is deprived of cGMP, an erection will not occur at all.

As PDE-5 inhibitors, Viagra, Cialis and Levitra help to counteract the effect of PDE-5 by blocking the enzyme. Hence, allowing for the level of cGMP to be raised during sexual stimulation and subsequently allowing for erection.

As the three drugs have similar mechanism of action, a question that would be raised is: Is buying Viagra online safely not the same as buying Cialis or Levitra?

Though they are similar in action, comparing the three drugs side by side would highlight some notable differences.

What are the differences between these three drugs?

Who are the manufacturers of these three drugs?

Real Viagra tablets are manufactured by Pfizer, while Cialis and Levitra are both manufactured by Eli Lilly and ICOS and GlaxoSmithKline and Bayer respectively.

What are the active ingredients in these drugs.

The active ingredient in Viagra tablets online is Sildenafil Citrate, while that of Cialis is tadalafil and Levitra is vardenafil hydrochloride.

What are the available doses for the drugs?
The best Viagra tablets come in doses of 25 mg, 50 mg, and 100 mg tablets, and should be taken an hour before sexual activity. Most patients are usually started on the 50 mg tablet, which could be either increased or decreased depending on the tolerance and / or effectiveness of the drug.

Cialis tablets come in 5 mg, 10 mg, and 20 mg tablets. Patients are usually started on the 10 mg tablets, which are either increased or decreased depending on the response of patients to the drug. Cialis tablets should be taken between 30 minutes to 12 hours before engaging in sex. However, the soft tabs of Cialis do not go through the digestion process and could be taken 15 minutes before having sex.

How long do the effects of the drugs last in the body?

Viagra: could take up to 4 hours before its effects wear off.
Cialis: Nicknamed the weekend pill because its effects can last for as long as 17 to 36 hours before wearing off.
Levitra: Takes up to 5 hours in the body.

Year of approval by the FDA:

Approval date for Viagra was the 27th of March, 1998.
Cialis was approved on the 1st of November, 2003.
Levitra was approved on the 20th of August, 2003.

How do the drugs look like?

Viagra is a small, diamond-shaped blue tablet with an engraving of the word ‘Pfizer’ in the middle.
Cialis is an almond-shaped, yellow tablet with a film coating.
Levitra tablet is orange in colour and has a flame logo.